Fig. 1: Hearing loss in Myh1−/− mice due to outer hair cell dysfunction. | Experimental & Molecular Medicine

Fig. 1: Hearing loss in Myh1−/− mice due to outer hair cell dysfunction.

From: MYH1 deficiency disrupts outer hair cell electromotility, resulting in hearing loss

Fig. 1

a Overall appearance of Myh1+/+, Myh1+/−, and Myh1−/− mice at postnatal Day 30. b Body weights of the Myh1+/+, Myh1+/−, and Myh1−/− mice. c Tone-pip ABR thresholds, d click ABR thresholds, and e ABR I/O functions of the Myh1+/+, Myh1+/−, and Myh1−/− mice at postnatal Day 30. f DPOAE thresholds and g DPOAE I/O functions at 6 kHz and h 30 kHz. b–h Myh1+/+ (black, n = 5), Myh1+/− (blue, n = 7), and Myh1−/− (red, n = 7) mice. The data are presented as the means ± SEMs. Statistical comparisons were performed using two-way ANOVA with Bonferroni correction for multiple comparisons in (b–h). **P < 0.01 and ***P < 0.001.

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