Table 6 Risk Ratios of allergic conditions associated with a quartile increase in phthalates and bisphenols mixture.

From: Phthalates and bisphenols early-life exposure, and childhood allergic conditions: a pooled analysis of cohort studies

 

N

Risk Ratio (95%CI)

Crude

Adjusteda

Prenatal analysis

 Asthma

1871

1.25 (1.02–1.54)

1.10 (0.83–1.46)

 Wheeze

2402

1.07 (0.98–1.18)

1.04 (0.93–1.16)

 Eczema

2116

1.33 (1.18–1.50)

0.95 (0.85–1.06)

 Rhinitis

1567

1.34 (1.20–1.50)

1.03 (0.89–1.19)

Postnatal analysis

 Asthma

1083

1.50 (1.19–1.90)

1.17 (0.91–1.50)

 Wheeze

1586

1.12 (1.01–1.24)

1.14 (1.02–1.26)

 Eczema

1574

0.93 (0.87–1.01)

0.98 (0.91–1.05)

 Rhinitis

1137

1.47 (1.18–1.83)

0.89 (0.68–1.17)

  1. Models obtained using quantile G-computation.
  2. aPrenatal analysis models adjusted for cohort membership, maternal age, ethnicity, parental education, marital status, family history of asthma, sex, prenatal tobacco smoke exposure, and season of birth. Postnatal analysis models were further adjusted for breastfeeding duration, age at outcome assessment, postnatal smoke exposure and gestational age.