Table 3 PDA treatment modality and neurodevelopmental and behavioral outcomes at 2 years of age.
Characteristics | n | Catheter closure n = 99 | n | Surgical ligation n = 279 | P-valuea |
|---|---|---|---|---|---|
Death/Severe NDI, n (%) | 81 | 40 (49) | 215 | 85 (40) | 0.13 |
Severe NDI, n (%) | 78 | 37 (47) | 197 | 67 (34) | 0.04 |
Death by follow-up, n (%) | 99 | 3 (3) | 279 | 18 (6) | 0.20 |
Moderate to severe cerebral palsy, n (%) | 81 | 13 (16) | 211 | 22 (10) | 0.19 |
BSID Cognitive Composite Score <70, n (%) | 80 | 31 (39) | 202 | 45 (22) | <0.01 |
BSID Language Composite Score <70, n (%) | 79 | 36 (46) | 196 | 64 (33) | 0.04 |
BSID Motor Composite Score <70, n (%) | 77 | 31 (40) | 199 | 56 (28) | 0.05 |
Blindness, n (%) | 81 | 2 (2) | 211 | 2 (1) | 0.32 |
Hearing impairment, n (%) | 80 | 3 (4) | 203 | 5 (2) | 0.56 |
Head circumference Z-score at follow-up, Median (IQR) | 81 | −0.9 (−1.6 to 0.3) | 206 | −0.9 (−1.7 to −0.1) | 0.10 |
NDI, n (%) | 79 | 63 (80) | 201 | 132 (66) | 0.02 |
BSID-III Cognitive Composite Score <85, n (%) | 80 | 58 (73) | 202 | 98 (49) | <0.01 |
BSID-III Language Composite Score <85, n (%) | 79 | 62 (78) | 196 | 120 (61) | 0.01 |
BSID-III Motor Composite Score <85, n (%) | 77 | 50 (65) | 199 | 112 (56) | 0.19 |
