Table 2 Characteristics of the subjects in the lung tissue study

From: Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition

Parameters

Non-smokers without COPD (n = 9)

Smokers without COPD (n = 10)

Smokers with COPD (n = 30)

p value

Female/male, n

3/6

3/7

11/19

0.925

Age, yrs

61.8 ± 3.7

63.8 ± 3.5

61.7 ± 1.2

0.790

Smokers, former/current, n

 

5/5

9/21

0.251

FEV1, %Predicted

94.7 ± 2.9

84.8 ± 2.7

49.5 ± 1.9

<0.001

FEV1/FVC, %

78.9 ± 1.5

75.3 ± 1.1

53.0 ± 1.8

<0.001

GOLD I–II/III–IV, n

NA

NA

12/18

NA

Cancer type, n

Squamous cell carcinoma

2

7

19

0.226

Adenocarcinoma

5

2

8

 

Small-cell lung cancer

2

1

3

 
  1. Values are mean ± SEM, unless otherwise stated
  2. COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume in 1, FVC forced vital capacity, NA not applicable
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