Fig. 2: Prognostic impact of ctDNA-high and high-risk PET variables.

Kaplan-Meier estimates of (A) PFS and (B) OS according to ctDNA levels. Patients with ctDNA levels ≤ 2.68 log hGE/mL are represented by the blue curves and patients with ctDNA levels > 2.68 log hGE/mL are represented by the red curves. Kaplan-Meier estimates of (C) PFS and (D) OS according to the presence of at least one PET/CT variable above the respective cut-off value (high-risk PET). Low-risk PET patients are represented by the blue curves and high-risk PET patients are represented by the red curves.