Table 1 Clinical and biological features of patients.

From: Clinical and transcriptomic characterization of patients with chronic lymphocytic leukemia harboring t(14;19): an ERIC study

 

Patients

Age (years)

Median ± sd

57 ± 12

Gender

 Female

41 (41%)

 Male

60 (59%)

Binet stage

 A

60 (59%)

 B

28 (28%)

 C

13 (13%)

IGHV status*

 M-IGHV

10 (12%)

 U-IGHV

75 (88%)

BCR stereotyped°

 Subset #8

12 (32%)

FISH+

 13q-

5 (5%)

 “Normal”

19 (20%)

 +12

55 (57%)

 11q-

8 (8%)

 17p-

9 (9%)

TP53 abn+

 Normal

83 (86%)

 Disrupted

13 (14%)

Karyotype

 No CK

48 (48%)

 CK3

53 (52%)

 CK5

20 (20%)

Richter transformation

 Cases

13 (13%)

  1. sd standard deviation, M-IGHV mutated IGHV gene, U-IGHV unmutated IGHV gene, 13q- 13q14 but interphase FISH analysis, 11q- del11q22-23 by interphase FISH analysis, 17p- 17p13 by interphase FISH analysis. TP53 abn TP53 abnormalities include deletions and/or mutations, CK3 complex karyotype, ⩾3 chromosome abnormalities, and CK5 = ⩾5 chromosome abnormalities, n.a. not available.
  2. * Data available from 85 patients. °Data available from 38 patients. + Data available from 96 patients.
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