Fig. 1: Design and working principle of the HTCMD.

a(i) The working schematic shows a cross-sectional view of the HTCMD, where chitosan droplets are expelled into the alginate solution under centrifugal force, leading to the formation of chitosan core-alginate shell microspheres. a(ii) Shows a top view of the device and a(iii) shows an isometric view. b The HTCMD is mounted on a motor shaft for controlled rotation, with the motor connected to a laptop for real-time management via an Arduino interface. A strobe light, synchronized with a camera, ensures accurate frame capture during microsphere production, while the laptop controls motor speed, camera functions, and data collection