Table 2 Comparison of ROS-based therapy and traditional therapy with advantages and limitations
Therapy | Methods | Advantages | Limitations | Ref. |
|---|---|---|---|---|
Traditional therapy | Surgery | Rapid tumor reduction, Curative for early-stage cancers | Highly traumatic, Incidence of complications, Risk of residual lesions, Can cause organ functional damage | |
Chemotherapy | Systemic treatment, Effective against metastatic cancers | Severe systemic side effects, Non-targeted drug delivery, Risk of drug resistance | ||
Radiotherapy | Non-invasive, Effective for localized tumor, Valid treatment for palliation | Damage to surrounding tissues, Risk of secondary cancers, Risk of radiation resistance | ||
Immunotherapy | Targeted approach, Long-lasting effects, High biosafety | Immune-related side effects, Variable effectiveness among patients | ||
ROS-based therapy | Photodynamic Therapy (PDT) | Minimally invasive, Minimized systemic toxicity, Minimal damage to surrounding tissues | Limited penetration depth, Rely on surrounding oxygen concentration | |
Sonodynamic Therapy (SDT) | Non-invasive, Deep penetration, Minimal damage to surrounding tissues | Require specific ultrasound parameters, Limited clinical availability | ||
Thermodynamic Therapy (TDT) | Not necessarily dependent on oxygen concentration, High compatibility in synergistic therapies | Risk of damage to surrounding healthy tissues, Require precise temperature control |
