Fig. 3 | Modern Pathology

Fig. 3

From: Fluorescence in situ hybridization (FISH) provides estimates of minute and interstitial BAP1, CDKN2A, and NF2 gene deletions in peritoneal mesothelioma

Fig. 3

Formalin-fixed paraffin-embedded series: Histological, Clinical, Immunohistochemical, and FISH features. Each column represents a patient. Rows indicate (from top to bottom): Histological type, Age at diagnosis, Sex, BAP1/MITF FISH, BAP1 immunohistochemistry, CDKN2A/ CEP9 FISH, P16 immunohistochemistry, MTAP immunohistochemistry, and NF2/PDGFB FISH. Patient cohort is presented according with the number of FISH ‘hits’ or abnormalities reported: BAP1, CDKN2A, NF2 triple hits: cases 1–14. BAP1 and CDKN2A double hits: cases 15–26. BAP1 and NF2 double hits cases 27–29. CDKN2A and NF2 double hits cases 30–35. BAP1 sole hits cases 36–49. CDKN2A sole hits cases 50–54. NF2 sole hits 55–57. No hits for all the remaining. Case #1 is the index case

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