Fig. 2: Examples of SNP-array results in melanoma and nevus. | Modern Pathology

Fig. 2: Examples of SNP-array results in melanoma and nevus.

From: Through the looking glass and what you find there: making sense of comparative genomic hybridization and fluorescence in situ hybridization for melanoma diagnosis

Fig. 2

a An example of nodular melanoma. b SNP-array plot of melanoma from a showing numerous gains and losses of segments of chromosomes. c An example of conventional nevus. d SNP-array plot of nevus from c showing no CNAs. e Aggregate frequency of CNAs in a series of 41 melanomas and 18 nevi from University of Michigan Dermatopathology database (frequency of gains (blue) and losses (red) on the vertical and chromosome locus on the horizontal). Top panel shows numerous gains and losses in melanomas. Bottom panel shows a low frequency of isolated abnormalities in nevi with isolated losses of 3p (red) and gains of 11p and 15q (blue).

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