Table 2 Reassessment of HER2 FISH results in ISH group 2 based on the 2018 ASCO/CAP guidelines.

From: A clinicopathological study of 30 breast cancer cases with a HER2/CEP17 ratio of ≥2.0 but an average HER2 copy number of <4.0 signals per cell

 

No. of cases

IHC result (No.)

Recounting FISH in cases scored IHC 2+ (No.)

    

HER2 negative

HER2 positive

ISH group 2

30

0

8

  

1+

15

  

2+

7

7

0

3+

0

  
  1. IHC immunohistochemistry, FISH fluorescence in situ hybridization.