Fig. 3: Examples of markedly reduced (null-like) p53 IHC staining observed in HPV-associated carcinomas. | Modern Pathology

Fig. 3: Examples of markedly reduced (null-like) p53 IHC staining observed in HPV-associated carcinomas.

From: p53 Immunohistochemical patterns in HPV-related neoplasms of the female lower genital tract can be mistaken for TP53 null or missense mutational patterns

Fig. 3

a Shows an invasive squamous cell carcinoma (SCC) involving the Bartholin gland (case 6) and “single cells” staining. b Shows a mucinous endocervical carcinoma (EDAC) with scattered “single cells” staining (case 46). c case 3, and d case 20, show scanty “clusters” of cells staining in invasive vulvar SCCs. e show “peripheral” staining in an EDAC (case 37).

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