Table 3 Morphological evaluation of borderline cases.

From: Transcriptomic data helps refining classification of pulmonary carcinoid tumors with increased mitotic counts

Characteristics

S8

S9

S10

S11

Necrosis

Present, focal

Present, focal

Absent

Present, focal

Architectural pattern

Trabecular

Solid, trabecular, rosettes

Solid, nested, trabecular

Rosettes, lobular with peripheral palisading

Average mitotic rate

13

14

17

26

Average Ki-67 (%)

18

23

15

58

RB1

Preserved expression

Preserved expression

Preserved expression

Preserved expression

P53

Wild-type

Wild-type

Wild-type

Wild-type