Table 1 Clinicopathological characteristics of low-grade appendiceal mucinous neoplasms by AJCC/TNM pathologic stage group.

From: Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms

 

pTisM0

pT3M0

pT4aM0

pTxM1a

pTxM1b

p value

(n = 66)

(n = 16)

(n = 16)

(n = 27)

(n = 67)

Univariate

Multivariate

Patient sex

  Female

43 (65.2%)

6 (37.5%)

6 (37.5%)

21 (77.8%)

43 (64.2%)

0.022

0.10

  Male

23 (34.8%)

10 (62.5%)

10 (62.5%)

6 (22.2%)

24 (35.8%)

Patient age (years)

  Mean ± SD

58.8 ± 16.2

58.4 ± 12.9

49.5 ± 11.5

56.2 ± 10.8

56.6 ± 12.5

0.17

0.26

  Median (range)

59.5 (19–91)

60 (34–75)

51 (23–74)

59 (27–77)

57 (30–90)

IBD (co-prevalence)

  Total (all subtypes)

7 (10.6%)

0 (0%)

0 (0%)

1 (3.7%)

1 (1.5%)

0.080

0.090

Index surgery

  Simple

47 (71.2%)

10 (62.5%)

8 (50.0%)

12 (44.4%)

24 (45.3%)

0.031

N/A

  Extensive

19 (28.8%)

6 (37.5%)

8 (50.0%)

15 (55.6%)

29 (54.7%)

Appendix: perforation

  Absent

62 (93.9%)

11 (68.8%)

9 (56.3%)

11 (45.8%)

27 (64.3%)

<0.001

0.001

  Present

4 (6.1%)

5 (31.3%)

7 (43.8%)

13 (54.2%)

15 (35.7%)

Appendix: margin

  Negative (R0)

62 (93.9%)

16 (100%)

14 (87.5%)

20 (87.0%)

34 (89.5%)

0.52

0.34

  Positive (R1)

4 (6.1%)

0 (0%)

2 (12.5%)

3 (13.0%)

4 (10.5%)

Peritoneal sampling

  Biopsies

3 (60.0%)

0 (0%)

0 (0%)

5 (18.5%)

16 (23.9%)

0.17

N/A

  Resection

2 (40.0%)

1 (100%)

6 (100%)

22 (81.5%)

51 (76.1%)

  1. SD standard deviation, IBD inflammatory bowel disease, N/A not applicable.
  2. Statistically significant p values (i.e., <0.05) are indicated in bold.