Table 1 Clinicopathological characteristics of low-grade appendiceal mucinous neoplasms by AJCC/TNM pathologic stage group.
From: Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms
pTisM0 | pT3M0 | pT4aM0 | pTxM1a | pTxM1b | p value | ||
|---|---|---|---|---|---|---|---|
(n = 66) | (n = 16) | (n = 16) | (n = 27) | (n = 67) | Univariate | Multivariate | |
Patient sex | |||||||
Female | 43 (65.2%) | 6 (37.5%) | 6 (37.5%) | 21 (77.8%) | 43 (64.2%) | 0.022 | 0.10 |
Male | 23 (34.8%) | 10 (62.5%) | 10 (62.5%) | 6 (22.2%) | 24 (35.8%) | ||
Patient age (years) | |||||||
Mean ± SD | 58.8 ± 16.2 | 58.4 ± 12.9 | 49.5 ± 11.5 | 56.2 ± 10.8 | 56.6 ± 12.5 | 0.17 | 0.26 |
Median (range) | 59.5 (19–91) | 60 (34–75) | 51 (23–74) | 59 (27–77) | 57 (30–90) | ||
IBD (co-prevalence) | |||||||
Total (all subtypes) | 7 (10.6%) | 0 (0%) | 0 (0%) | 1 (3.7%) | 1 (1.5%) | 0.080 | 0.090 |
Index surgery | |||||||
Simple | 47 (71.2%) | 10 (62.5%) | 8 (50.0%) | 12 (44.4%) | 24 (45.3%) | 0.031 | N/A |
Extensive | 19 (28.8%) | 6 (37.5%) | 8 (50.0%) | 15 (55.6%) | 29 (54.7%) | ||
Appendix: perforation | |||||||
Absent | 62 (93.9%) | 11 (68.8%) | 9 (56.3%) | 11 (45.8%) | 27 (64.3%) | <0.001 | 0.001 |
Present | 4 (6.1%) | 5 (31.3%) | 7 (43.8%) | 13 (54.2%) | 15 (35.7%) | ||
Appendix: margin | |||||||
Negative (R0) | 62 (93.9%) | 16 (100%) | 14 (87.5%) | 20 (87.0%) | 34 (89.5%) | 0.52 | 0.34 |
Positive (R1) | 4 (6.1%) | 0 (0%) | 2 (12.5%) | 3 (13.0%) | 4 (10.5%) | ||
Peritoneal sampling | |||||||
Biopsies | 3 (60.0%) | 0 (0%) | 0 (0%) | 5 (18.5%) | 16 (23.9%) | 0.17 | N/A |
Resection | 2 (40.0%) | 1 (100%) | 6 (100%) | 22 (81.5%) | 51 (76.1%) | ||