Fig. 1: Renal oncocytoma with adverse pathology.
From: Renal oncocytoma with adverse pathologic features: a clinical and pathologic study of 50 cases
Renal oncocytoma tumors are formed predominantly of solid (A), nested (B), and tubulocystic (C) architectures. Areas of cellular discohesiveness between tumor cells are seen (D). The stroma is only minimally present at the periphery (A) but is edematous and paucicellular centrally (C and D). The tumor shows minimal to mild nuclear pleomorphism with inconspicuous nucleoli occasionally seen (E). Focal “degenerative” atypia, nuclear hyperchromasia (F), and binucleation are seen (inset).
