Fig. 1: Pipeline of data analyses. | Molecular Psychiatry

Fig. 1: Pipeline of data analyses.

From: Effects of sleep on the glymphatic functioning and multimodal human brain network affecting memory in older adults

Fig. 1

A Collecting magnetic resonance imaging (MRI) and polysomnographic (PSG) data from older adults. B Constructing the functional connectivity network (FCN) and structural connectivity network (SCN), and calculating the coupling between them (i.e., SC-FC coupling; upper right panel) based on resting-state functional MRI (R-fMRI) and diffusion MRI (dMRI) data. Calculating the Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) index (lower right panel) based on dMRI data. C Partial correlation analyses between DTI-ALPS and FCN, SCN, or their coupling. D Mediation analyses of glymphatic functioning on relationship between sleep quality and multimodal human brain networks. E Sleep-related neural mechanism of memory function.

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