Fig. 2: Comparison of genetic architecture for childhood maltreatment. | Molecular Psychiatry

Fig. 2: Comparison of genetic architecture for childhood maltreatment.

From: Genetic architectures of childhood maltreatment and causal influence of childhood maltreatment on health outcomes in adulthood

Fig. 2

a Observed scale SNP-based heritability. We performed the linkage disequilibrium score regression (LDSC) to estimate the observed scale SNP-based heritability of childhood maltreatment. The x axis represents the childhood maltreatment, and the y axis represents the SNP-based heritability. Error bars (black line) are 95% confidence intervals. b Pairwise genetic correlation for childhood maltreatment in combined sexes. c Pairwise genetic correlation for childhood maltreatment in males. d Pairwise genetic correlation for childhood maltreatment in females. In panel b–d, * indicates the P-value < 0.0033 (Bonferroni corrected significance level = 0.05/15 = 0.0033), and lines show the dendrogram of the hierarchical clustering based on average linkage and Euclidean distance.

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