Fig. 4: Functional enrichment analysis and network visualization. | Molecular Psychiatry

Fig. 4: Functional enrichment analysis and network visualization.

From: Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics

Fig. 4

a, c: GO and KEGG pathway enrichment for AMDD1 a and AMDD2 subtypes c. The bar chart displays significantly enriched BP and pathways, with red bars representing PLS+ genes and blue bars representing PLS- genes. Numbers inside bars indicate gene counts in each pathway. Statistical significance is shown on the x-axis as -log10(p-value), with longer bars indicating stronger significance (pFDR < 0.05). b, d: Chord diagram illustrating the relationships between enriched pathways and genes in the AMDD1b and AMDD2 d. Node size and color represent gene count and pathway category, respectively.

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