Fig. 5: Functional and cellular specificity of MSN-associated genes.

a. The distribution of regional gene expression maps of seven brain cells using ssGSEA scores. b. The number of overlapping genes with AMDD1 PLS1 + weighted genes for each cell type. c. Enrichment results for AMDD1 overlapped PLS1+ genes. d. The number of overlapping genes with AMDD1 PLS1 - weighted genes for each cell type. e. Enrichment results for AMDD1 overlapped PLS1- genes. f. The number of overlapping genes with AMDD2 PLS1 + weighted genes for each cell type. g. Enrichment results for AMDD2 overlapped PLS1+ genes. Asterisks (*) indicate statistical significance (p-perm < 0.05) for cell-type enrichment.