Table 1 Subject basic information.

From: Postmortem tissue biomarkers of menopausal transition

Group

Pre-menopausal

Peri-menopausal

Post-menopausal

N

10

21

11

Age (years)*

26 (17–39)

49.6 (45–55)

62.7 (56–67)

Education (years)

15 (11–18)

13 (10–18)

14.5 (11–20)

BMI

33.4 (17.4–62.5)

31.1 (19.6–65.9)

27.7 (17.6–44.3)

Race (%Black/White/Other)

40/60/0%

29/62/9%

36/64/0%

Hormonal contraceptive use

40%

14%

0%

Hormone replacement therapy

0%

10%

9%

PMI (hours)

28.25 (14.5–42)

28.5 (13–74.5)

28 (14–44.2)

Hypothalamus RIN

5.0 (2.6–5.8)

5.1 (2.6–6.2)

5.1 (2.7–6.2)

Pituitary RIN

6.1 (5.3–6.7)

5.8 (3.2–6.7)

6.0 (5.2–6.7)

% Axis I confident

30%

67%

45%

% MDD/Depression

20%

52%

45%

% Anxiety

10%

0%

18%

% Substance use

30%

43%

0%

% Antidepressant use

9%

25%

20%

  1. Age, education, BMI, PMI, and RIN values are displayed as mean (range). There was a statistically significant difference in age between the groups (*p < 0.05, one-way ANOVA), but no differences in other parameters.
  2. BMI body mass index, PMI post-mortem interval, RIN the RNA integrity number.