Table 1 Participating sites.
Cohort | N HC | N MDD | Age HC (mean ± SD) | Age MDD (mean ± SD) | N females in HC (%) | N females in MDD (%) | Ethnicity White/Black/Asian/Other/NA HC | Ethnicity White/Black/Asian/Other/NA MDD |
|---|---|---|---|---|---|---|---|---|
AFFDIS | 44 | 33 | 39.98 ± 14.63 | 39.58 ± 15.42 | 20 (45.5%) | 14 (42.4%) | NA | NA |
Barcelona-StPau | 32 | 62 | 46.03 ± 8.13 | 46.98 ± 7.75 | 23 (71.9%) | 49 (79%) | 16/0/0/0/16 | 62/0/0/0/0 |
CARDIFF | 0 | 39 | NA | 46.67 ± 12.02 | NA | 26 (66.7%) | NA | NA |
CSAN | 49 | 60 | 33.2 ± 12.19 | 35.92 ± 13.49 | 34 (69.4%) | 40 (66.7%) | NA | NA |
Calgary | 52 | 56 | 15.81 ± 5.08 | 18.15 ± 2.53 | 29 (55.8%) | 32 (57.1%) | 22/0/5/4/7 | 23/1/0/1/19 |
DCHS | 70 | 22 | 31.46 ± 6.88 | 28.77 ± 6.34 | 70 (100%) | 22 (100%) | 0/66/0/0/4 | 0/21/0/0/1 |
FIDMAG | 34 | 36 | 45.94 ± 11.67 | 48.61 ± 12.94 | 22 (64.7%) | 22 (61.1%) | 34/0/0/0/0 | 36/0/0/0/0 |
FOR2107Marburg | 411 | 327 | 34.76 ± 12.78 | 35.6 ± 12.82 | 257 (62.5%) | 208 (63.6%) | 411/0/0/0/0 | 327/0/0/0/0 |
FOR2107Munster | 221 | 174 | 28.34 ± 10.32 | 35.87 ± 12.92 | 140 (63.3%) | 109 (62.6%) | 221/0/0/0/0 | 174/0/0/0/0 |
Hiroshima | 169 | 150 | 39.88 ± 12.39 | 44.25 ± 11.99 | 104 (61.5%) | 71 (47.3%) | 0/0/169/0/0 | 0/0/150/0/0 |
Houston | 186 | 108 | 26.75 ± 15.97 | 32.31 ± 16.46 | 104 (55.6%) | 66 (61.1%) | 76/11/5/93/2 | 63/7/0/37/1 |
MODECT | 0 | 27 | NA | 74.11 ± 9.81 | NA | 18 (66.7%) | NA | 0/0/0/0/27 |
MOODS | 32 | 64 | 35.12 ± 12.9 | 34.25 ± 12.45 | 21 (65.6%) | 44 (68.8%) | 25/1/2/0/0 | 45/11/4/0/0 |
Melbourne | 9 | 22 | 20.67 ± 3.54 | 19.64 ± 3.11 | 3 (33.3%) | 17 (77.3%) | 0/0/0/0/9 | 2/0/0/0/20 |
Minnesota | 40 | 70 | 15.68 ± 2 | 15.36 ± 1.84 | 26 (65%) | 53 (75.7%) | 25/1/3/11/0 | 49/7/1/13/0 |
Moraldilemma | 46 | 24 | 18.5 ± 1.77 | 19.42 ± 2.19 | 46 (100%) | 24 (100%) | 20/2/14/2/8 | 18/0/4/2/0 |
Munster | 723 | 282 | 35.36 ± 12.14 | 37.68 ± 12.03 | 413 (57.1%) | 164 (58.2%) | 723/0/0/0/0 | 282/0/0/0/0 |
NESDA | 65 | 154 | 40.29 ± 9.74 | 37.19 ± 10.49 | 42 (64.6%) | 103 (66.9%) | 63/0/0/0/2 | 139/0/0/0/15 |
QTIM | 286 | 100 | 21.99 ± 3.37 | 22.09 ± 3.17 | 184 (64.3%) | 74 (74%) | 286/0/0/0/0 | 100/0/0/0/0 |
UCSF | 90 | 77 | 15.29 ± 1.29 | 15.61 ± 1.37 | 43 (47.8%) | 51 (66.2%) | 26/2/7/54/1 | 15/6/2/54/0 |
SanRaffaele | 0 | 128 | NA | 49.84 ± 10.97 | NA | 84 (65.6%) | NA | 128/0/0/0/0 |
SHIP_START | 443 | 136 | 55.44 ± 12.82 | 53.59 ± 11.72 | 198 (44.7%) | 96 (70.6%) | 443/0/0/0/0 | 136/0/0/0/0 |
SHIP_TREND | 937 | 312 | 50.64 ± 14.28 | 49.20 ± 12.15 | 409 (43.6%) | 203 (65.1%) | 937/0/0/0/0 | 312/0/0/0/0 |
Sexpect | 20 | 20 | 33.75 ± 7.2 | 38.25 ± 11.63 | 3 (15%) | 8 (40%) | NA | NA |
Singapore | 17 | 23 | 38.53 ± 4.64 | 39.3 ± 8.34 | 9 (52.9%) | 10 (43.5%) | 0/0/17/0/0 | 0/0/23/0/0 |
Socat_dep | 99 | 79 | 36.55 ± 13.65 | 39.66 ± 12.89 | 89 (89.9%) | 71 (89.9%) | 99/0/0/0/0 | 79/0/0/0/0 |
StanfFAA | 18 | 14 | 30.44 ± 10.25 | 35.63 ± 8.44 | 18 (100%) | 14 (100%) | 6/2/1/3/6 | 8/2/2/0/2 |
StanfT1wAggr | 59 | 56 | 37.24 ± 10.52 | 37.11 ± 10.18 | 36 (61%) | 33 (58.9%) | NA | NA |
TAD | 0 | 39 | NA | 16.03 ± 1.15 | NA | 29 (74.4%) | NA | 24/2/7/5/1 |
TIGER | 11 | 49 | 15.18 ± 1.08 | 15.73 ± 1.4 | 5 (45.5%) | 33 (67.3%) | NA | NA |
Jena (TiPs) | 76 | 28 | 47.7 ± 16.14 | 43.36 ± 12.04 | 35 (46.1%) | 14 (50%) | NA | NA |
Cohort | Antidepressant free / users MDD | First / recurrent episode MDD | Remitted / acute episode MDD | BDI total score MDD (mean ± SD) | HDRS total score MDD (mean ± SD) | Age of onset MDD (mean ± SD) |
|---|---|---|---|---|---|---|
AFFDIS | 1/76 | NA | 0/77 | 19.22 ± 14.07 | 9.88 ± 7.06 | NA |
Barcelona-StPau | 4/58 | 22/40 | 23/39 | NA | 13.66 ± 8.18 | 33.16 ± 11.43 |
CARDIFF | 0/39 | 0/34 | 0/39 | 36.16 ± 9.33 | 19.58 ± 4.76 | 28.94 ± 14 |
CSAN | 31/29 | 14/46 | 0/60 | NA | NA | NA |
Calgary | 38/18 | 19/37 | 0/56 | 26.67 ± 11.53 | 19.16 ± 6.66 | 14.33 ± 3.2 |
DCHS | NA | NA | NA | NA | NA | NA |
FIDMAG | 4/31 | 11/23 | 1/35 | NA | 24.69 ± 5.78 | 37.06 ± 13.57 |
FOR2107Marburg | 124/203 | 93/200 | 76/251 | 18.67 ± 10.82 | 8.06 ± 6.42 | 27.38 ± 13.42 |
FOR2107Munster | 72/102 | 63/108 | 59/115 | 16.85 ± 11.72 | 9.72 ± 7.35 | 24.75 ± 11.15 |
Hiroshima | 10/138 | 74/74 | 0/150 | 29.79 ± 9.39 | 18.67 ± 5.58 | 38.16 ± 13.25 |
Houston | 105/1 | 21/43 | 39/37 | 16.5 ± 15.12 | 9.87 ± 7.93 | 21.57 ± 10.7 |
MODECT | 19/8 | 0/22 | 0/27 | NA | NA | NA |
MOODS | 64/0 | 32/32 | 0/64 | NA | 26.56 ± 5.37 | 28.25 ± 11.54 |
Melbourne | 19/3 | 7/15 | 0/22 | NA | NA | 15.71 ± 3.85 |
Minnesota | 52/16 | 16/22 | 6/0 | 25.85 ± 12.12 | NA | 12.39 ± 2.39 |
Moraldilemma | 24/0 | 8/16 | 0/24 | NA | NA | NA |
Munster | 27/231 | 64/216 | 23/258 | 25.63 ± 10.18 | 18.96 ± 4.3 | 29.35 ± 11.78 |
NESDA | 98/56 | 67/87 | 0/154 | NA | NA | 24.17 ± 10.96 |
QTIM | 70/30 | NA | NA | NA | NA | 18.42 ± 3.4 |
UCSF | 77/0 | 32/36 | 7/61 | 26.68 ± 11.78 | NA | 13.25 ± 2.24 |
SanRaffaele | 7/120 | 12/116 | 17/111 | 14.88 ± 8.05 | 20.26 ± 6.76 | 35.61 ± 12.32 |
SHIP_START | 113/23 | 77/59 | NA | 11.56 ± 10.30 | NA | 38.01 ± 13.05 |
SHIP_TREND | 258/54 | 113/199 | NA | 12.45 ± 8.11 | NA | 36.19 ± 14.27 |
Sexpect | 0/20 | 4/16 | 0/20 | 20.86 ± 12.4 | 12.9 ± 5.11 | 30.87 ± 11.24 |
Singapore | 5/18 | 8/15 | NA | NA | 6.3 ± 6.23 | 32.73 ± 9.51 |
Socat_dep | 41/38 | 19/60 | 33/46 | 24.01 ± 12.14 | 13.29 ± 7.55 | 31.63 ± 16.67 |
StanfFAA | 11/3 | 0/14 | 0/14 | 28.29 ± 9.98 | 18.86 ± 4.22 | 16.29 ± 6.83 |
StanfT1wAggr | 27/20 | 6/48 | 0/56 | 25.76 ± 9.99 | 14.38 ± 5.84 | 19.52 ± 9.24 |
TAD | 24/15 | 24/9 | 0/39 | NA | NA | 12 ± 2.52 |
TIGER | 29/20 | 29/20 | 0/49 | NA | NA | 12.12 ± 2.49 |
Jena | 10/18 | 5/23 | NA | 21.26 ± 11.71 | NA | NA |
