Fig. 5: Simulations of optimal target location maximizing overlap with the convergent depression circuit. | Neuropsychopharmacology

Fig. 5: Simulations of optimal target location maximizing overlap with the convergent depression circuit.

From: Targeting depression circuitry with H1 coil Transcranial Magnetic Stimulation: a retrospective circuit mapping study

Fig. 5

A Overlap between H1 E-field (thresholded to include the top 1% of voxels) with the convergent depression circuit, evaluated at different simulated coil locations. The coil center was systematically shifted in 5 mm increments along anterior (25–55 mm), lateral (20 mm) and medial (20 mm) directions from the MNI motor hotspot coordinate [−42,−16,65]. B Simulated target locations for the currently used target, the optimal target with maximal overlap, and the boundary delineating locations of lower overlap are projected onto the scalp using SimNIBS. MNI Montreal Neurological Institute.

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