Fig. 3: CRF knockdown in the BNST did not alter sucrose self-administration. | Neuropsychopharmacology

Fig. 3: CRF knockdown in the BNST did not alter sucrose self-administration.

From: Disentangling the effects of corticotrophin releasing factor and GABA release from the bed nucleus of the stria terminalis on ethanol self-administration in mice

Fig. 3

A There was no significant effect of CRF knockdown among active lever responses in males self-administering sucrose (Male GFP n = 13, Cre n = 10). B There was no significant difference between virus conditions in females in active lever responding for sucrose (Female GFP n = 7, Cre n = 6). C There was no significant difference between virus conditions in males in rewards earned (Male GFP n = 13, Cre n = 10). D There was no significant difference between virus conditions in females in rewards earned (Female GFP n = 7, Cre n = 6). E CRF knockdown did not affect rewards earned in the arithmetic progressive ratio test. Females had higher motivation to work for sucrose reinforcers on this schedule. F CRF knockdown did not alter rewards earned in the exponential progressive ratio test. Females had higher motivation to work for sucrose reinforcers on this schedule.

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