Fig. 4: Upset analysis of gene expression in primary malignant cells with del17p.
From: Deletion of 17p in cancers: Guilt by (p53) association
Gene expression in primary malignant cells with or without del17p was compared (with DESeq2), focusing on genes located on 17p that were downregulated in del17p cells. Set size refers to the number of genes showing change in cells from the indicated cancers. Intersection size refers to the shared genes between the different cancers analysed. Cells from 5 cancers were compared; laml acute myeloid leukaemia, prad prostate adenocarcinoma, paad pancreatic adenocarcinoma, brca breast invasive carcinoma, coad colorectal adenocarcinoma. The data for analysis was taken from cBioPortal.
