Table 1 Common genes affected by LOH and haploinsufficiency in cells with del17p.
From: Deletion of 17p in cancers: Guilt by (p53) association
Gene | Essential CRISPR | Essential RNAi | TSG | Position on 17p | Chromosome band |
|---|---|---|---|---|---|
GLOD4 | 757097 | 17p13.3 | |||
TIMM22 | Yes | No | 997129 | 17p13.3 | |
YWHAE | 1344275 | 17p13.3 | |||
INPP5K | 1494577 | 17p13.3 | |||
PITPNA | 1517718 | 17p13.3 | |||
PRPF8 | Yes | Yes | 1650629 | 17p13.3 | |
WDR81 | 1716523 | 17p13.3 | |||
SMYD4 | Yes | 1779485 | 17p13.3 | ||
RPA1 | Yes | Yes | Yes | 1829702 | 17p13.3 |
DPH1 | Yes | 2030112 | 17p13.3 | ||
SRR | 2303378 | 17p13.3 | |||
SGSM2 | 2337498 | 17p13.3 | |||
METTL16 | Yes | No | 2405562 | 17p13.3 | |
PAFAH1B1 | Yes | Yes | Yes | 2593183 | 17p13.3 |
CTNS | 3636459 | 17p13.2 | |||
ITGAE | 3714628 | 17p13.2 | |||
P2RX1 | 3896592 | 17p13.2 | |||
ATP2A3 | 3923870 | 17p13.2 | |||
ZZEF1 | 4004445 | 17p13.2 | |||
CYB5D2 | 4143168 | 17p13.2 | |||
UBE2G1 | 4269259 | 17p13.2 | |||
MED11 | Yes | Yes | 4731428 | 17p13.2 | |
PSMB6 | Yes | Yes | 4796144 | 17p13.2 | |
SLC25A11 | 4937130 | 17p13.2 | |||
SPAG7 | 4959226 | 17p13.2 | |||
NUP88 | Yes | Yes | 5359668 | 17p13.2 | |
RPAIN | Yes | No | 5419641 | 17p13.2 | |
C1QBP | 5432777 | 17p13.2 | |||
DERL2 | 5471254 | 17p13.2 | |||
MIS12 | Yes | No | 5486285 | 17p13.2 | |
KIAA0753 | 6578147 | 17p13.1 | |||
ACADVL | 7217125 | 17p13.1 | |||
DVL2 | 7225342 | 17p13.1 | |||
PHF23 | Yes | 7235029 | 17p13.1 | ||
GABARAP | Yes | 7240008 | 17p13.1 | ||
CTDNEP1 | Yes | No | 7243591 | 17p13.1 | |
ELP5 | Yes | No | 7251416 | 17p13.1 | |
NEURL4 | 7315628 | 17p13.1 | |||
ACAP1 | 7336529 | 17p13.1 | |||
TMEM256 | 7402975 | 17p13.1 | |||
ZBTB4 | Yes | 7459366 | 17p13.1 | ||
POLR2A | Not done | Yes | 7484366 | 17p13.1 | |
SENP3 | 7561919 | 17p13.1 | |||
MPDU1 | 7583529 | 17p13.1 | |||
FXR2 | 7591230 | 17p13.1 | |||
SAT2 | 7626234 | 17p13.1 | |||
TP53 | Yes | 7661779 | 17p13.1 | ||
WRAP53 | 7686071 | 17p13.1 | |||
KDM6B | 7834217 | 17p13.1 | |||
NAA38 | Yes | No | 7856685 | 17p13.1 | |
KCNAB3 | 7921859 | 17p13.1 | |||
TRAPPC1 | Yes | No | 7930345 | 17p13.1 | |
CNTROB | 7932081 | 17p13.1 | |||
ALOXE3 | 8095900 | 17p13.1 | |||
VAMP2 | 8159147 | 17p13.1 | |||
PFAS | 8247608 | 17p13.1 | |||
SLC25A35 | 8287763 | 17p13.1 | |||
KRBA2 | 8356902 | 17p13.1 | |||
RPL26 | Yes | No | 8377516 | 17p13.1 | |
STX8 | 9250471 | 17p13.1 | |||
SCO1 | 10672474 | 17p13.1 | |||
ZNF18 | 11977439 | 17p12 | |||
MAP2K4 | Yes | 12020829 | 17p12 | ||
ELAC2 | Yes | No | 12894929 | 17p12 | |
COX10 | 14069490 | 17p12 | |||
ZSWIM7 | 15976560 | 17p12 | |||
TTC19 | 15999784 | 17p12 | |||
NCOR1 | 16029065 | 17p11.2 | |||
COPS3 | Yes | Yes | 17246616 | 17p11.2 | |
PEMT | 17505563 | 17p11.2 | |||
TOM1L2 | Yes | 17843511 | 17p11.2 | ||
ATPAF2 | 17977409 | 17p11.2 | |||
GID4 | 18039408 | 17p11.2 | |||
DRG2 | 18087892 | 17p11.2 | |||
ALKBH5 | 18183078 | 17p11.2 | |||
AKAP10 | 19904302 | 17p11.2 |
