Fig. 2: Transcriptomic rewiring of cancer and host cells. | Oncogenesis

Fig. 2: Transcriptomic rewiring of cancer and host cells.

From: Transcriptomic profiling of co-cultured cancer-host cells identifies hypoxia as a driver of the skeletal muscle cell’s anti-proliferative effect on cancer cells

Fig. 2

A Schematic representation of FACS sorting of monocultures and co-cultures. B PCA plot of the different cell groups identified after mRNA sequencing (n = 4). C Scatter dot plot showing the distribution of up- and downregulated genes in each comparison (number of DEGs is shown in the figure). D–I Dot plots of enriched hallmarks from gene set enrichment analysis (GSEA). The color of the dot indicates statistical significance.

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