Fig. 6: Mean expression of core clock and clock-associated genes in HUVECs from preterm and term neonates by birth weight.
From: Circadian clock activity in human umbilical vein endothelial cells of preterm and term neonates

Mean expression of 8 core clock (a) and 10 clock-associated genes (b) normalized to four control genes (GAPDH, PPIA, HPRT1, PSMB2) in HUVEC samples from infants with a BW > 2500 g (n = 6), 2500–1500 g (n = 4), 1499–1000 g (n = 3) and <1000 g (n = 4). Cells were synchronized and sampled over a 24–52 h time period, then averaged by pooling equal RNA amounts from each time point. The mean gene expression was not statistically different between subgroups classified according to birth weight. Dotted line combine data points of the same gene product. The complete data set can be found in Supplementary Data 5.