Table 1 Demographic data and clinical characteristics of the study population, assigned to subgroups according to the subject’s birth weight. (*without ELBW infants).
From: Circadian clock activity in human umbilical vein endothelial cells of preterm and term neonates
Demographic data | Group 1 Birth weight >2500 g (n = 26) | Group 2 LBW 1500–2500 g (n = 18) | Group 3* VLBW 1001–1499 g (n = 7) | Group 4 ELBW ≤1000 g (n = 9) |
|---|---|---|---|---|
Birth weight (g), median (range) | 3342 (2515–4210) | 1950 (1620–2460) | 1170 (1100–1490) | 700 (430–920) |
Gestational age at birth (weeks + days), median (range) | 38 + 4 (35 + 2–40 + 0) | 33 + 5 (29 + 3–38 + 0) | 29 + 1 (28 + 0–32 + 6) | 24 + 6 (23 + 1–26 + 2) |
Sex, female, n (%) | 12 (46) | 6 (33.3) | 5 (71.4) | 5 (55.6) |
Twin child, n (%) | 3 (11.5) | 7 (38.9) | 6 (85.7) | 4 (44.4) |
Antenatal glucocorticoids, n (%) ACT < 48 h before birth, n (%) | 0 | 11 (61.1) 4 (22.2) | 7 (100) 1 (14.3) | 9 (100) 2 (22.2) |
Mode of delivery, n (%) | ||||
• Primary cesarean section | 20 (76.9) | 5 (27.8) | 0 | 0 |
• Secondary cesarean section | 4 (15.4) | 5 (27.8) | 6 (85.7) | 7 (77.8) |
• Vaginal | 2 (7.7) | 8 (44.4) | 1 (14.3) | 2 (22.2) |
Gestational and perinatal disorders, n (%) | ||||
Intrauterine growth restriction | 0 | 2 (11.1) | 3 (42.9) | 2 (22.2) |
Premature rupture of membranes or placenta praevia bleeding | 3 (11.5) | 7 (38.9) | 3 (42.9) | 7 (77.8) |
Maternal diabetes (gestational, type I, type II) | 4 (15.3) | 1 (5.6) | 0 | 0 |
Early-onset infection (diagnosed by IL-6 plasma concentration at birth >100 pg/mL) | 2 (7.6) | 2 (11.1) | 2 (28.6) | 5 (55.6) |
