Table 1 Demographic characteristics and hospital course.
From: Neonatal intermittent hypoxemia events are associated with later systemic hypertension
No HTN (n = 126) | HTN (n = 38) | p-value | ||
|---|---|---|---|---|
Antenatal characteristics | ||||
Race (n (%)) | Black/African American | 75/126 (59.5%) | 19/38 (50.0%) | 0.66* |
White/Caucasian | 46/126 (36.5%) | 18/38 (47.4%) | ||
North American Indian/Native Alaskan | 1/126 (0.8%) | 0/38 (0.0%) | ||
Asian | 2/126 (1.6%) | 0/38 (0.0%) | ||
Mixed | 2/126 (1.6%) | 1/38 (2.6%) | ||
Hispanic ethnicity (n (%)) | 5/126 (4.0%) | 0/38 (0.0%) | 0.48* | |
Maternal age (median (IQR)) | 28 (23,33) | 28 (23,32) | 0.77 | |
Maternal education (n (%)) | Did not graduate HS | 20/126 (15.9%) | 2/37 (5.4%) | 0.13* |
HS graduate | 34/126 (27.0%) | 5/37 (13.5%) | ||
Any College | 35/126 (27.8%) | 18/37 (48.6%) | ||
Trade School | 11/126 (8.7%) | 2/37 (5.4%) | ||
Associate Degree | 11/126 (8.7%) | 3/37 (8.1%) | ||
College Graduate | 11/126 (8.7%) | 5/37 (13.5%) | ||
Graduate Degree | 4/126 (3.2%) | 2/37 (5.4%) | ||
Tobacco during pregnancy (n (%)) | 19/126 (15.1%) | 7/38 (18.4%) | 0.59 | |
GA weeks (median (IQR)) | 28.7 (27.0, 29.9) | 28.3 (25.6, 29.6) | 0.21 | |
GA < 29 weeks (n (%)) | 69/126 (54.8%) | 21/38 (55.3%) | 0.93 | |
Birth weight (median (IQR)) | 1120 (838, 1390) | 1130 (798, 1405) | 0.80 | |
SGA status (n (%)) | 9/126 (7.1%) | 2/38 (5.3%) | 0.70 | |
Apgar 1 min (median (IQR)) | 4 (2,6) | 4 (2,5) | 0.41 | |
Apgar 5 min (median (IQR)) | 7 (6,8) | 7 (5,8) | 0.49 | |
Male sex (n (%)) | 62/126 (49.2%) | 20/38 (52.6%) | 0.67 | |
Multiple birth (n (%)) | 37/126 (29.4%) | 7/38 (18.4%) | 0.22 | |
Antenatal steroids (n (%)) | 120/125 (96.0%) | 34/38 (89.5%) | 0.14 | |
Chorioamnionitis (n (%)) | 19/126 (15.1%) | 3/38 (7.9%) | 0.26 | |
Hospital course characteristics | ||||
Received surfactant (n (%)) | 79/126 (62.7%) | 28/38 (73.7%) | 0.23 | |
UAC present (n (%)) | 53/126 (42.1%) | 20/38 (52.6%) | 0.24 | |
Sepsis prior to 34 wks’ PMA (n (%)) | 11/126 (8.7%) | 3/38 (7.9%) | 0.89 | |
Caffeine prior to 34 wks’ PMA (n (%)) | 121/126 (96.0%) | 36/38 (94.7%) | 0.66 | |
Early HUS IVH Grade 3 or 4 (n (%)) | 6/126 (4.8%) | 1/38 (2.6%) | 0.59 | |
Chest Tube placed prior to 34 wks’ PMA (n (%)) | 3/126 (2.4%) | 1/38 (2.6%) | 0.88 | |
PDA diagnosed by echocardiogram prior to 34 wks’ PMA (n (%)) | 36/126 (28.6%) | 12/38 (31.6%) | 0.66 | |
SCr ≥ 1 between 14 DOL and 34.0 wks’ PMA (n (%)) | 8/126 (6.3%) | 2/38 (5.3%) | 0.79 | |
SCr ≥ 0.5 between 14 DOL and 34.0 wks’ PMA (n (%)) | 70/126 (55.6%) | 21/38 (55.3%) | 0.97 | |
Days on oxygen prior to 34.0 wks’ PMA (median (IQR)) | 19 (6, 41) | 31 (6, 51) | 0.09 | |
Days with mechanical ventilation prior to 34.0 wks’ PMA (median (IQR)) | 2 (0,9) | 2 (1, 22) | 0.37 | |
Renal imaging performed <36.0 wks’ PMA (n (%)) | 22/126 (17.5%) | 7/38 (18.4%) | 0.89 | |
Renal imaging findings (n (%)) | Normal | 12/22 (54.5%) | 6/7 (85.7%) | 0.62* |
Echogenicity and pyelectasis | 2/22 (9.1%) | 0/7 (0.0%) | ||
Pyelectasis (no echogenicity) | 2/22 (9.1%) | 1/7 (14.3%) | ||
Echogenicity (no pyelectasis) | 4/22 (18.2%) | 0/7 (0.0%) | ||
Renal Calculi | 1/22 (4.5%) | 0/7 (0.0%) | ||
Hydronephrosis | 1/22 (4.5%) | 0/7 (0.0%) | ||
Ventilation at 36 wks’ PMA (n (%)) | Mechanical ventilation | 11/126 (8.7%) | 5/38 (13.2%) | 0.86 |
Non-invasive ventilation | 9/126 (7.1%) | 2/38 (5.3%) | ||
Nasal cannula >2 L | 2/126 (1.6%) | 2/38 (5.3%) | ||
Nasal cannula <=2 L | 26/126 (20.6%) | 7/38 (18.4%) | ||
No respiratory support | 78/126 (61.9%) | 22/38 (57.9%) | ||
Oxygen supplementation at 36 wks’ PMA | 39/126 (31.0%) | 14/38 (36.8%) | 0.85 | |
Diuretics at 34–36 wks’ PMA (n (%)) | 28/126 (22.2%) | 10/38 (26.3%) | 0.50 | |
Clinically apparent BP 34–36 wks’ PMA (n (%)) | – | 5/38 (13.2%) | – | |
