Fig. 3: Imaging findings of a 59-year-old patient with biopsy-proven Gleason 7 (3 + 4) prostate cancer treated by transperineal MRgFLA. | Prostate Cancer and Prostatic Diseases

Fig. 3: Imaging findings of a 59-year-old patient with biopsy-proven Gleason 7 (3 + 4) prostate cancer treated by transperineal MRgFLA.

From: New kids on the block: MRI guided transrectal focused US, TULSA, focal laser ablation, histotripsy – a comprehensive review

Fig. 3

A Pre-treatment axial T2-weighted fast spin‒echo MRI (repetition time (TR)/echo time (TE), 7990/97) and B Corresponding diffusion weighted Image (DWI) image, b 1600 s/mm2, acquired on a 3T Siemens Skyra Fit scanner, showing the tumor in the right mid gland peripheral zone (arrows). C Intraoperative MRI obtained on a 1.5T GE Excite Twinspeed scanner showing the contoured rectal wall (orange line), prostate margin (blue outline) and region of interest (red outline) with 5 mm and 10 mm margins (maroon outline). D MRI thermography image during treatment showing heat deposition color coded in green overlaid on the contoured region of interest. E Axial gadovist-enhanced MRI obtained immediately post-treatment showing the de-vascularized ablated volume (arrows). F T2-weighted fast spin‒echo MRI (TR/TE, 7990/97) obtained 6 months following the ablation on the same scanner, showing involution and volume loss at the treated area (arrow). Findings from a targeted biopsy of the treatment zone at 6 months were negative.

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