Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Pyroptosis in health and disease: mechanisms, regulation and clinical perspective

Fig. 6

Potential targeted therapeutic strategies for pyroptosis in non-cancer diseases. Investigations into pyroptosis enhance our understanding of the pathological mechanisms underlying various diseases. Key elements involved in pyroptosis, including NLRP3, caspase-1, gasdermin D, and upstream molecules such as TLR4/NF-κB axis, are crucial for human health and have led to the development of numerous targeted therapies for several inflammatory conditions. The figure was created by Figdraw

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