Fig. 5
From: Engineered mitochondria in diseases: mechanisms, strategies, and applications
Strategies for artificial mitochondrial transfer. Physical methods for facilitating the transplantation of free mitochondria into cells include coculture, microinjection, magnetomitotransfer, mito-ception, mitopunch, fluidFM, photothermal nanoblade, optical tweezers, droplet microfluidics, etc. These methods utilize natural intercellular mitochondrial transfer or apply additional driving forces using various devices. Biochemical methods involve utilizing mitochondrial surface modifications or vectors for delivering mitochondria, including exosomes, polymer coatings, targeting peptides, and so on. (Generated by the authors with Adobe Illustrator)
