Fig. 6

Summary of the characteristics of small nucleic acid drugs used in clinical trials. a Various administration routes for small nucleic acid drugs, including subcutaneous, intravitreal, intravenous, inhalation, and oral administration. Blue box: in a clinical trial; green box: on the market; red box: delisted. b Administration routes of small nucleic acid drugs on the market. c Administration routes of small nucleic acid drugs in clinical trials. d Different phases of clinical trials for small nucleic acid drugs. e Different target organs of small nucleic acid drugs in clinical trials