Fig. 5 | Signal Transduction and Targeted Therapy

Fig. 5

From: Sulfide regulation and catabolism in health and disease

Fig. 5

Summary of agonists and inhibitors targeting CBS, CSE and 3-MST. CBS activity can be enhanced by the agonist S-adenosylmethionine (AdoMet), while its inhibition is mediated by compounds such as Podocarpusflavone A, Sikokianin C, 2”,4”-Di-O-(Z-p-coumaroyl)afzelin, Agathisflavone, Cupressuflavone, 3’-Hydroxy-Volkensiflavon and Benserazide. CSE activity is stimulated by Norswertianolin (NW) and inhibited by I157172 and NSC4056. For 3-MST, inhibition is achieved by Rutin and Compounds 1, 2, 3, and 5

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