Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions

Fig. 2

Diagram of the structural model of nuclear receptors. Nuclear receptors share four functional domains: the N-terminal transcription activation domain (NTD), the DNA binding domain (DBD), the ligand binding domain (LBD), and a hinge domain (H) that connects the DBD and LBD. Some NRs also contain a highly variable C-terminal transcription activation domain (CTD)

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