Table 2 Study outcomes.

From: Traumatic spinal cord injury and its correlation to risk of autoimmune/-inflammatory disease

 

Incidence rate ratios of autoimmune disease associated with traumatic spinal cord injury

     

1: Basic adjustmentA

2: CCI adjustedB

Fully adjustedC

Auoimmune disease group

Exposure status

N

PYD

Rate; 1000−1

 

Incidence rate ratio (95% CI)

 

All incident types

TSCI

236

50,865

4.6

1.81 (1.59 to 2.05)

1.53 (1.35 to 1.74)

1.32 (1.16 to 1.50)

 

Non-TSCI

274,314

1.4

2.0

1.00 reference

1.00 reference

1.00 reference

Endocrine & haematologic

TSCI

14

50,865

0.28

0.88 (0.52 to 1.48)

0.79 (0.47 to 1.33)

0.72 (0.43 to 1.22)

 

Non-TSCI

39,125

1.4

0.28

1.00 reference

1.00 reference

1.00 reference

Gastroenterologic

TSCI

42

50,865

0.83

1.42 (1.05 to 1.92)

1.22 (0.90 to 1.66)

1.06 (0.78 to 1.43)

 

Non-TSCI

65,220

1.4

0.47

1.00 reference

1.00 reference

1.00 reference

DM-1E

TSCI

55

47,803

1.2

2.01 (1.54 to 2.61)

1.39 (1.07 to 1.81)

1.13 (0.87 to 1.47)

 

Non-TSCI

51,846

1.2

0.45

1.00 reference

1.00 reference

1.00 reference

Iridocyclitis

TSCI

7

50,865

0.14

0.86 (0.41 to 1.80)

0.80 (0.38 to 1.69)

0.70 (0.34 to 1.48)

 

Non-TSCI

14,449

1.4

0.11

1.00 reference

1.00 reference

1.00 reference

MSF

TSCI

27

59,836

0.54

3.70 (2.54 to 5.40)

3.46 (2.37 to 5.04)

3.23 (2.21 to 4.71)

 

Non-TSCI

15,709

1.1

0.15

1.00 reference

1.00 reference

1.00 reference

Dermatologic

TSCI

37

50,865

0.73

2.57 (1.86 to 3.55)

2.26 (1.63 to 3.11)

1.90 (1.37 to 2.62)

 

Non-TSCI

28,164

1.4

0.20

1.00 reference

1.00 reference

1.00 reference

Other neurologic

TSCI

10

50,865

0.20

5.19 (2.79 to 9.65)

4.37 (2.35 to 8.14)

3.71 (1.99 to 6.91)

 

Non-TSCI

4273

1.4

0.03

1.00 reference

1.00 reference

1.00 reference

Systemic

TSCI

47

50,865

0.92

1.92 (1.44 to 2.55)

1.73 (1.30 to 2.30)

1.50 to (1.13 to 2.00)

 

Non-TSCI

53,838

1.4

0.39

1.00 reference

1.00 reference

1.00 reference

  1. AAdjusted for age, calendar year and sex.
  2. BAdjusted for age, calendar year, sex, and modified Charlson Comorbidity Index.
  3. CAdjusted for age, calendar year, sex, modified Charlson Comorbidity Index, and hospitalization for (bacterial/viral/other) infections.
  4. DPerson years for non-traumatic spinal cord injury population presented in 108 exponent.
  5. EStudy period from 1988-2018.
  6. FStudy population included from age of 12 years to let statistical model converge.
  7. PY Person years, TSCI Traumatic spinal cord injury, DM-1 Diabetes mellitus type 1, MS Multiple Sclerosis, CCI Charlson Comorbidity Index, N counts, CI Confidence interval.
  8. For specification of autoimmune disease groups: See supplementary 2.
Back to article page