Table 2 Top 10 DMR’s Average Regional Beta Value Difference (ARBVD) in ACE categories.

From: Effect of parental adverse childhood experiences on intergenerational DNA methylation signatures from peripheral blood mononuclear cells and buccal mucosa

ARBVD

FDR

Gene Name

Chr

Start

End

No.CpGs

Low

 −0.12

3.6e-26

N/A

chr18

77376639

77377589

5

 −0.10

2.7e-06

N/A

chr8

49427275

49427415

3

 −0.09

7.3e-08

PTPRN2

chr7

157369895

157369960

3

 0.09

5.8e-06

N/A

chr9

100881931

100881995

2

 −0.09

4.7e-10

PON1

chr7

94953653

94954202

8

 0.09

7.6e-06

N/A

chr10

101282726

101282883

4

 0.09

7.2e-08

MPRIP

chr17

17109640

17109817

7

 −0.08

5.5e-07

AC01657.3

chr2

239140032

239140318

5

 0.08

4.9e-10

MAFK

chr7

1572252

1572327

2

 0.08

1.5e-05

HDAC4

chr2

240241154

240241218

2

Moderate

 0.13

3.9e-05

CYP4V2

chr4

187125958

187126073

2

 −0.12

6.2e-09

N/A

chr6

36639949

36640019

2

 −0.11

1.8e-05

N/A

chr8

49427275

49427415

3

 0.10

1.1e-11

AC006033.22

chr7

38350921

38351226

5

 −0.09

9.1e-09

N/A

chr18

77377119

77377589

3

 −0.09

2.6e-18

KIR3DL1

chr19

55280672

55281274

5

 −0.08

1.7e-11

KCNN3

chr1

154839909

154839983

2

 −0.08

2.7e-05

PON1

chr7

94953653

94954202

8

 0.07

1.4e-06

N/A

chrX

8751330

8751402

2

 0.07

2.6e-06

FMOD

chr1

203320506

203320541

2

High

 0.11

1.7e-06

NA

chr15

56299380

56299382

2

 −0.09

1.7e-05

LINC01044

chr13

112978683

112978703

2

 −0.08

1.8e-09

KCNN3

chr1

154839813

154839983

3

 0.08

6.5e-06

FLG-AS1

chr1

152161885

152161927

2

 −0.06

1.0e-07

BAIAP2L1

chr7

98029266

98029285

3

 −0.06

2.8e-09

NA

chr2

88469730

88469819

4

 −0.06

4.8e-12

FAM194A

chr3

150421255

150421424

3

 0.06

6.6e-06

NA

chrX

8751266

8751402

3

 0.05

6.5e-06

NA

chr6

28853021

28853050

2

 −0.05

7.3e-08

HLA-C

chr6

31239243

31239411

5

  1. The top ten highest magnitude of ARBVD significant DMRs displayed in each of the ACE categories. The ARBVD is a region defined by DMRcate() as a group of CpGs (>1) with a stable beta value difference between each of the ACE groups and control, adjusted for the variables in our linear model. “NA” refers to genic regions without annotation by DMRcate().