Fig. 6: Independent PRM analysis of the abnormally expressed proteins in the four groups (CON, CSDS, NOR-treated CSDS, and IMI-treated CSDS) to confirm the bioinformatic analysis. | Translational Psychiatry

Fig. 6: Independent PRM analysis of the abnormally expressed proteins in the four groups (CON, CSDS, NOR-treated CSDS, and IMI-treated CSDS) to confirm the bioinformatic analysis.

From: Quantitative proteomics combined independent PRM analysis reveals the mitochondrial and synaptic mechanism underlying norisoboldine’s antidepressant effects

Fig. 6

Protein extracts of prefrontal cortex from the mice of the four groups, CON, CSDS, NOR-treated CSDS, and IMI-treated CSDS were examined by PRM analysis. Mitochondrial proteins Cox7c, Mrp142, Naa30, Ighm, Apoa4, Ssu72, Mrps30, Apoh, Acbd5, and Cdv3 and synaptic proteins, including Dcx, Fam3c, Arid1b, and Rnf112 showed significant difference (N = 4–6 per group, *p < 0.05, **p < 0.01; #p < 0.05).

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