Table 1 Top 20 differentially methylated genes in the whole blood of PND1 guinea pigs exposed to ACS.
Gene name | DMCs | % Change (range) | % Change (avg) | Localization |
---|---|---|---|---|
Msmo1 | 5 | 23.6 ~ 36.7 | 33.21 | Gene body |
Adamts17 | 3 | 29.5 ~ 31.5 | 30.25 | Gene body |
Taf4b | 1 | 30.0 | 30.00 | Promoter |
Parp12 | 2 | 20.5, 29.8 | 25.12 | Gene body |
Padi2 | 4 | −9.4 ~ 41.8 | 20.28 | Promoter; gene body |
Slco3a1 | 4 | 9.5 ~ 27.5 | 18.88 | Gene body |
Igsf21 | 4 | 12.0 ~ 23.4 | 18.44 | Gene body |
Bcam | 1 | −18.2 | −18.18 | Gene body |
Slc45a1 | 1 | −17.6 | −17.55 | Promoter; gene body |
Stab2 | 2 | 10.9 ~ 24.0 | 17.47 | Gene body |
Wrap73 | 3 | −36.7 ~ 6.4 | −16.69 | Gene body |
Kcnh2 | 1 | 14.66 | 14.66 | Promoter; gene body |
Il12rb1 | 2 | 13.7, 15.3 | 14.51 | Gene body |
Rreb1 | 1 | 14.5 | 14.46 | Gene body |
Efcab10 | 1 | 14.0 | 14.02 | Gene body |
Il1rl2 | 2 | 7.2, 20.0 | 13.59 | Gene body |
Nphp4 | 11 | −17.1 ~ −5.3 | −12.82 | Gene body |
Pbxip1 | 11 | 7.9 ~ 16.9 | 12.77 | Gene body |
Echdc2 | 1 | 12.7 | 12.69 | Gene body |
Zbtb20 | 1 | 12.6 | 12.59 | Gene body |
Prkd2 | 1 | 12.6 | 12.55 | Promoter |