Fig. 7: Music prevents damage to synaptic plasticity in the mPFC. | Translational Psychiatry

Fig. 7: Music prevents damage to synaptic plasticity in the mPFC.

From: Music therapy as a preventive intervention for postpartum depression: modulation of synaptic plasticity, oxidative stress, and inflammation in a mouse model

Fig. 7

A Volcano plot of differentially expressed genes. B Venn diagram of differentially expressed genes. C Heatmaps of the cluster analysis data. D GO analysis. E KEGG analysis. F, G Expression levels of Eya4 and Lhx8 mRNA in the mPFC. All values are presented as the means ± SEMs. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post-hoc test for multiple comparisons. The normality of the data was assessed using the Shapiro-Wilk test, and F test was used to compare variances between groups. n = 6 per group. All significant differences were compared with those in the PPD group. *(#,^)P < 0.05; **(##,^^)P < 0.01; ***(###,^^^)P < 0.001. (mPFC: medial prefrontal cortex, GO: Gene Ontology, KEGG: Kyoto Encyclopedia of Genes and Genomes).

Back to article page