Table 1 Means and standard deviations (in parentheses) of demographics, phenotypic and clinical raw scores for all three groups of the replication dataset.

From: Using the excitation/inhibition ratio to optimize the classification of autism and schizophrenia

 

TD

AT

SZ

AT v. SZ v. TD

AT > TD

SZ > AT

SZ > TD

Males/Females

26/29

25/5

31/8

χ2(2) = 15.8, <0.001

χ2(1) = 9.1, 0.003

χ2(1) = 0.01, 0.9

χ2(1) = 8.62, 0.003

    

F(2, 121), p

t(df), p, pFDR

t(df), p, pFDR

t(df), p, pFDR

Age

23.86 (3.73)

22.33 (3.74)

25.66 (3.58)

8.31, < 0.000

−1.98 (79.8), 0.051, 0.08

4.06 (76.9), <0.001, 0

2.46 (88), 0.016, 0.02

CPZ

–

151.2 (528)

362.11 (371.75)

–

–

–

–

FD

0.08 (0.03)

0.09 (0.04)

0.11 (0.1)

5.23, 0.007

2.52 (66.6), 0.014, 0.03

0.772 (69.6), 0.443, 0.52

2.71 (54.3), 0.009, 0.01

est. IQ

112.26 (14.62)

109.1 (15.21)

99.41 (13.34)

9.366, <0.001

−1.33 (82.8), 0.186, 0.27

−3.26 (77), 0.002, 0.01

−4.97 (90.5), <0.001, 0

EQ

49 (10.28)

33.57 (11.1)

39.8 (12.26)

22.37, <0.001

−6.73 (72.2), <0.001, 0

2.50 (73.9), 0.015, 0.03

−3.65 (72.2), <0.001, 0

ADOS Total

1.87 (1.45)

10.1 (2.61)

8.41 (5.26)

78.26, < 0.000

17.5 (52.2), <0.001, 0

−1.67 (58.8), 0.72, 0.78

7.62 (44.2), <0.001, 0

BVAQ Verbalizing

18.55 (5.51)

22.2 (4.54)

22 (5.03)

7.02, 0.001

3.07 (81.4), 0.003, 0.01

0.0571 (75.1), 0.955, 0.96

3.22 (90.4), 0.002, 0

BVAQ Fantasizing

19.69 (5.12)

17.9 (6.03)

21.36 (5.48)

4, 0.02

−1.17 (73.5), 0.247, 0.31

2.72 (75.2), 0.008, 0.02

1.88 (82.8), 0.064, 0.07

BVAQ Identifying

15.53 (4.82)

18.57 (6.4)

20.41 (4.96)

10.43, <0.001

2.59 (63), 0.012, 0.03

1.29 (68.2), 0.203, 0.29

4.79 (85.2), <0.001, 0

BVAQ Emotionalizing

22.38 (3.74)

21.83 (3.51)

22.56 (4.2)

0.6, 0.55

−0.810 (81.4), 0.421, 0.47

1.07 (74), 0.289, 0.38

0.389 (77.9), 0.698, 7

BVAQ Analyzing

17.91 (4.43)

18.47 (4.27)

19.9 (4.5)

2.81, 0.6

0.576 (81.9), 0.566, 0.57

1.62 (76), 0.11, 0.18

2.27 (85.4), 0.026, 0.03

PANSS Positive

 

12.1 (2.86)

15.36 (4.86)

  

3.88 (66.96), <0.001, 0

 

PANSS Negative

 

15.57 (4.7)

19.26 (6.2)

  

2.644 (72.75), 0.01, 0.02

 

PANSS General

 

26.7 (5.62)

31.59 (6.98)

  

3.716 (73), <0.001, 0

 
  1. Group statistics are shown in the last four columns. Pairwise comparisons were performed using Welch two-samples t test. Both uncorrected (i.e., p) and false discovery rate corrected (i.e., pFDR) p values are shown.
  2. CPZ chlorpromazine equivalent in mg, FD framewise displacement, est. IQ estimated Intelligence Quotient, EQ empathy quotient, ADOS autism diagnostic observation schedule module 4, BVAQ bermond–vorst alexithymia questionnaire.
  3. The bold results were statistically significant.
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