Table 3 Group differences in Hurst exponent (H) per component, in the Replication dataset, computed using ANCOVA with age, sex, IQ, and FD as covariates.

From: Using the excitation/inhibition ratio to optimize the classification of autism and schizophrenia

Adjusted H mean (SE)

IC no.

TD

AT

SZ

F (2, 117)

p

pfdr

ηp2

Post hoc

SUBCORTICAL DOMAIN

1

Caudate 1

1.1 (0.02)

0.98 (0.03)

0.99 (0.03)

2.55

0.08

0.18

0.04

–

2

Subthalamus/hypothalamus

0.8 (0.02)

0.83 (0.03)

0.75 (0.03)

2.38

0.1

0.2

0.04

–

3

Putamen

0.98 (0.02)

0.97 (0.03)

0.93 (0.03)

1

0.36

0.56

0.02

–

4

Caudate 2

0.98 (0.02)

0.95 (0.03)

0.97 (0.03)

0.01

0.6

0.78

0.01

–

5

Thalamus

0.94 (0.02)

0.91 (0.03)

0.85 (0.03)

2.8

0.07

0.18

0.05

–

AUDITORY DOMAIN

6

Superior temporal gyrus

0.99 (0.02)

0.96 (0.03)

1 (0.03)

0.99

0.37

0.56

0.02

–

7

Middle temporal gyrus

0.91 (0.02)

0.93 (0.03)

0.93 (0.03)

0.33

0.72

0.86

0.01

–

SENSORIMOTOR DOMAIN

8

Postcentral gyrus 1

1.35 (0.02)

1.3 (0.03)

1.27 (0.03)

2.55

0.08

0.18

0.04

–

9

Left postcentral gyrus

1.29 (0.02)

1.21 (0.3)

1.15 (0.03)

6.18

0.003

0.02

0.1

TD > SZ**

10

Paracentral lobule 1

1.19 (0.02)

1.12 (0.04)

1.04 (0.03)

6.25

0.003

0.02

0.1

TD > SZ**

11

Right postcentral gyrus

1.3 (0.03)

1.25 (0.04)

1.16 (0.03)

4.57

0.01

0.05

0.7

TD > SZ**

12

Superior parietal lobule

1.2 (0.02)

1.16 (0.03)

1.1 (0.03)

2.8

0.07

0.18

0.05

–

13

Paracentral lobule 2

1.11 (0.02)

1.07 (0.03)

1.01 (0.03)

3

0.05

0.16

0.05

TD > SZ*

14

Precentral gyrus

1.22 (0.02)

1.2 (0.03)

1.14 (0.03)

2.78

0.07

0.18

0.05

–

15

Superior parietal lobule

1.25 (0.02)

1.23 (0.03)

1.21 (0.03)

0.5

0.61

0.78

0.008

–

16

Postcentral gyrus 2

1.28 (0.02)

1.24 (0.03)

1.21 (0.03)

1.93

0.15

0.28

0.03

–

VISUAL DOMAIN

17

Calcarine gyrus

1.3 (0.02)

1.2 (0.03)

1.18 (0.03)

6.23

0.003

0.02

0.1

TD > SZ**

18

Middle occipital gyrus

1.17 (0.02)

1.12 (0.03)

1.04 (0.03)

5.76

0.004

0.03

0.09

TD > SZ**

19

Middle temporal gyrus

1.19 (0.02)

1.14 (0.03)

1.06 (0.03)

6.33

0.003

0.02

0.1

TD > SZ**

20

Cuneus

1.26 (0.02)

1.19 (0.03)

1.16 (0.03)

3.79

0.03

0.13

0.06

TD > SZ*

21

Right middle occipital gyrus

1.17 (0.02)

1.11 (0.03)

1.03 (0.03)

8.46

<0.001

0

0.13

TD > SZ***

22

Fusiform gyrus

1 (0.02)

0.98 (0.03)

0.95 (0.02)

3

0.05

0.16

0.05

TD > SZ*

23

Inferior occipital gyrus

1.11 (0.02)

1.1 (0.03)

0.97 (0.03)

8.25

<0.001

0

0.12

TD > SZ***

24

Lingual gyrus

1.24 (0.02)

1.15 (0.03)

1.08 (0.03)

7.9

<0.001

0

0.12

TD > SZ***

25

Middle temporal gyrus

1 (0.02)

0.99 (0.03)

0.96 (0.03)

2.69

0.7

0.86

0.04

–

COGNITIVE CONTROL DOMAIN

26

Inferior parietal lobule 1

1.37 (0.02)

1.37 (0.02)

1.39 (0.02)

0.29

0.75

0.86

0.01

–

27

Insula

1.03 (0.02)

1.01 (0.02)

1 (0.02)

0.7

0.5

0.73

0.01

–

28

Superior medial frontal gyrus

1.15 (0.02)

1.13 (0.03)

1.15 (0.03)

0.24

0.78

0.86

0.004

–

29

Inferior frontal gyrus

1.12 (0.02)

1.1 (0.02)

1.11 (0.02)

0.18

0.83

0.88

0.003

–

30

Right inferior frontal gyrus

1.19 (0.02)

1.16 (0.02)

1.19 (0.02)

0.63

0.54

0.73

0.01

–

31

Middle frontal gyrus

1.18 (0.02)

1.16 (0.02)

1.15 (0.02)

0.48

0.62

0.78

0.01

–

32

Inferior parietal lobule 2

1.35 (0.02)

1.32 (0.02)

1.31 (0.02)

1.63

0.2

0.33

0.03

–

33

Left inferior parietal lobule

1.29 (0.02)

1.28 (0.03)

1.28 (0.02)

0.08

0.93

0.93

0.001

–

34

Supplementary motor area

1.25 (0.02)

1.17 (0.02)

1.23 (0.02)

5.1

0.008

0.05

0.08

TD > AT**

35

Superior frontal gyrus

1.21 (0.02)

1.18 (0.02)

1.22 (0.02)

1.4

0.25

0.4

0.02

–

36

Middle frontal gyrus 1

1.1 (0.02)

1.1 (0.03)

1.1 (0.03)

0.21

0.81

0.88

0.004

–

37

Hippocampus 1

0.78 (0.02)

0.79 (0.03)

0.77 (0.02)

0.13

0.88

0.91

0.002

–

38

Left inferior parietal lobule

1.28 (0.02)

1.21 (0.02)

1.26 (0.02)

2.62

0.08

0.18

0.04

–

39

Middle cingulate cortex

0.99 (0.02)

0.97 (0.03)

0.92 (0.03)

2.37

0.1

0.2

0.04

–

40

Inferior frontal gyrus

1.11 (0.02)

1.05 (0.03)

1.04 (0.02)

3.37

0.04

0.15

0.06

–

41

Middle frontal gyrus 2

1.06 (0.02)

1.04 (0.03)

0.99 (0.03)

1.73

0.18

0.32

0.03

–

42

Hippocampus 2

0.83 (0.02)

0.84 (0.03)

0.81 (0.03)

0.29

0.75

0.86

0.01

–

DEFAULT MODE DOMAIN

43

Precuneus 1

1.23 (0.02)

1.19 (0.02)

1.19 (0.02)

1.7

0.19

0.32

0.03

–

44

Precuneus 2

1.15 (0.02)

1.13 (0.02)

1.1 (0.02)

2

0.14

0.27

0.03

–

45

Anterior cingulate cortex 1

1.09 (0.02)

1.08 (0.02)

1.06 (0.02)

0.62

0.54

0.73

0.01

–

46

Posterior cingulate cortex 1

0.96 (0.02)

0.97 (0.03)

0.98 (0.03)

0.26

0.77

0.86

0.004

–

47

Anterior cingulate cortex 2

1.04 (0.02)

1.05 (0.03)

1.03 (0.03)

0.12

0.89

0.91

0.002

–

48

Precuneus 3

1.17 (0.02)

1.14 (0.03)

1.11 (0.02)

1.8

0.17

0.31

0.03

–

49

Posterior cingulate cortex 2

1.35 (0.02)

1.37 (0.02)

1.34 (0.02)

0.63

0.54

0.73

0.01

–

CEREBELLAR DOMAIN

50

Cerebellum 1

0.98 (0.02)

0.93 (0.03)

0.89 (0.03)

2.71

0.07

0.18

0.04

–

51

Cerebellum 2

1.09 (0.02)

1.02 (0.03)

1 (0.03)

3.49

0.03

0.13

0.06

TD > SZ*

52

Cerebellum 3

0.9 (0.02)

0.9 (0.03)

0.81 (0.03)

3.25

0.04

0.15

0.05

TD > SZ*

53

Cerebellum 4

1 (0.02)

0.96 (0.03)

0.93 (0.03)

2.99

0.05

0.16

0.05

TD > SZ*

  1. Multiple comparison correction of the ANCOVA p values was performed using false discovery rate (fdr). The ANCOVA effect size was calculated using partial η2. Post hoc tests were ran using Tukey’s HSD Test for multiple comparisons with C.I. = 95%.
  2. * p < 0.05; ** p < 0.01; *** p < 0.001.
  3. The bold results were statistically significant.
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