Fig. 7: The impact of predefined genes associated with various disorders on functional connectivity density (FCD) changes.

a Partial least square (PLS) regression weights assigned to genes linked with different disorders with FCD changes, with asterisks denoting significant differences between patients with schizophrenia and those with other disorders (*p < 0.05; **p < 0.01). b Proportion of disorder-related genes whose expression profiles and FCD changes are significantly correlated. MDD, major depression disorder; AD, Alzheimer’s disease; ASD, autism; EP, epilepsy; ID, intellectual disability; PD, Parkinson’s disease.