Table 1 GCA coefficient differences between OCD patients at baseline and healthy controls.
ROIs | Brain regions | MNI (X, Y, Z) | T value | Cluster size | Breakdown |
|---|---|---|---|---|---|
Left dorsal caudate | |||||
X-to-Y | |||||
OCD > HC | R Cerebellum Crus II/I | 27 −84 −36 | 4.61 | 64 | 40/24 |
Y-to-X | |||||
OCD > HC | L/R Precuneus | 0 −69 39 | 5.00 | 40 | 36/4 |
R/L MCC/SMA | 3 3 42 | 4.26 | 29 | 18/6/3/2 | |
R SFG/MFG | 27 6 57 | 5.29 | 24 | 17/7 | |
OCD < HC | L SFG/MFG/mSFG | −6 57 39 | −4.28 | 33 | 13/10/10 |
Right dorsal caudate | |||||
X-to-Y | |||||
/ | / | / | / | / | / |
Y-to-X | |||||
OCD > HC | R/L MCC/SMA | 12 3 39 | 4.92 | 51 | 29/12/7/3 |
L SFG/MFG | −21 12 48 | 4.98 | 40 | 26/14 | |
Left ventral caudate | |||||
X-to-Y | |||||
OCD < HC | L/R Precuneus, L MCC, and L/R SPG | −3 −57 57 | −5.53 | 219 | 122/79/13/4/1 |
Y-to-X | |||||
OCD > HC | L/R Precuneus, L MCC/SPG/Cuneus, and R MCC | −12 −75 48 | 5.46 | 211 | 111/53/29/13/3/2 |
R MFG/SFG | 21 12 51 | 5.11 | 47 | 29/18 | |
R MFG/SFG/IFG (triangular part) | 27 36 36 | 5.25 | 46 | 36/8/2 | |
L SMG/IPG | −54 −45 36 | 3.93 | 25 | 14/11 | |
L SFG/MFG | −21 12 51 | 4.32 | 25 | 21/4 | |
Left ventral caudate | |||||
Y-to-X | |||||
OCD > HC | R MTG/STG | 51 −60 18 | 4.17 | 24 | 23/1 |
L MFG/IFG (opercular part)/IFG (triangular part) | −42 18 33 | 4.36 | 21 | 10/9/2 | |
Right ventral caudate | |||||
X-to-Y | |||||
OCD < HC | L/R Precuneus and L MCC | 0 −57 54 | −4.62 | 95 | 51/41/3 |
Y-to-X | |||||
OCD > HC | L MCC and L/R Precuneus | −3 −45 45 | 4.87 | 35 | 13/13/9 |
R OC/Rectus/SFG (orbital part) | 12 12 −18 | 4.95 | 25 | 15/7/3 | |
R MFG/SFG | 27 33 36 | 4.43 | 25 | 21/4 | |
R Thalamus | 9 −12 3 | 4.29 | 22 | 22 | |
R MTG | 45 −60 15 | 4.87 | 22 | 22 | |
L/R Precuneus | 0 −54 54 | 4.21 | 21 | 13/8 | |
Left dorsolateral putamen | |||||
X-to-Y | |||||
OCD < HC | L/R ACC and R MCC | −6 30 −9 | −4.24 | 69 | 43/23/3 |
Y-to-X | |||||
OCD > HC | L/R ACC and R mOFC | 6 36 0 | 5.30 | 96 | 54/36/6 |
Right dorsolateral putamen | |||||
X-to-Y | |||||
/ | / | / | / | / | / |
Y-to-X | |||||
/ | / | / | / | / | / |
Left ventromedial putamen | |||||
X-to-Y | |||||
OCD < HC | R/L MCC/SMA | 3 −15 42 | −4.74 | 68 | 49/16/3/1 |
Y-to-X | |||||
OCD > HC | R/L MCC/SMA | 9 0 36 | 4.55 | 49 | 28/17/3/1 |
L/R ACC | −3 36 12 | 4.62 | 38 | 23/15 | |
R MFG/IFG (triangular part)/SFG | 30 30 27 | 4.73 | 35 | 24/9/2 | |
Right ventromedial putamen | |||||
X-to-Y | |||||
OCD < HC | L ACC, R mSFG, L mOFC, R ACC, and R mSFG | 6 60 9 | −4.50 | 64 | 39/17/3/3/2 |
Y-to-X | |||||
OCD > HC | L ACC, R/L mSFG, and R ACC | 3 57 9 | 4.19 | 24 | 10/9/4/1 |
R MFG/SFG | 27 33 36 | 4.52 | 20 | 11/9 | |
Left globus pallidus | |||||
X-to-Y | |||||
/ | / | / | / | / | / |
Y-to-X | |||||
/ | / | / | / | / | / |
Right globus pallidus | |||||
X-to-Y | |||||
/ | / | / | / | / | / |
Y-to-X | |||||
/ | / | / | / | / | / |
Left nucleus accumbens | |||||
X-to-Y | |||||
OCD < HC | L/R ACC and R mOFC | −3 33 −3 | −5.06 | 35 | 28/5/2 |
Y-to-X | |||||
OCD > HC | L/R ACC and R mOFC | −3 33 −3 | 5.84 | 47 | 27/14/6 |
Right nucleus accumbens | |||||
X-to-Y | |||||
/ | / | / | / | / | / |
Y-to-X | |||||
/ | / | / | / | / | / |
