Fig. 4: Polygenic profiles underlying A-DCCA identified white matter regions. | Translational Psychiatry

Fig. 4: Polygenic profiles underlying A-DCCA identified white matter regions.

From: Deep adversarial learning identifies ADHD-specific associations between apoptotic genes and white matter microstructure in frontal-striatum-cerebellum circuit

Fig. 4

A, B Correlations between p-PRS and DTI metrics in two models. A Dendrite development P-PRS scores were associated with FA values in the AA-DCCA region; B In the SA regions, synapse p-PRSs were associated with RD and AD values (right and left), neuron migration p-PRSs were related to MD values (middle). C the correlations between dendrite p-PRS and AA-DCCA region differed among ADHD and TD groups. D best-fit R2 in each pathway in two models (asterisk * denotes significant adjust P-values).

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