Table 1 Top 10 SNPs contributed to each A-DCCA model.

From: Deep adversarial learning identifies ADHD-specific associations between apoptotic genes and white matter microstructure in frontal-striatum-cerebellum circuit

CHR

BP

SNP

A1

Saliency score

Gene

Biological process

Top 10 genetic contributors to AA-DCCA

22

45724727

rs6007592

A

0.95967615

FAM118A

Protein binding

22

38581503

rs4821754

C

0.81379056

PLA2G6

Intracellular Membrane-Associated Calcium-Independent

2

100109001

rs6715321

C

0.7096488

REV1

DNA biosynthetic process

10

12762476

rs723210

C

0.6532598

CAMK1D

Apoptotic process/regulation of dendrite development

11

28498509

rs10835345

C

0.65170395

METTL15

Apoptotic process/rRNA base methylation

17

12005251

rs11078050

A

0.6466721

MAP2K4

Positive regulation of neuron apoptotic process

4

112228994

rs6822712

C

0.6425801

Intergenic

NA

1

67186429

rs17129381

C

0.6179403

SGIP1

Endocytosis

17

12018851

rs76321211

C

0.61320865

MAP2K4

Positive regulation of neuron apoptotic process

11

28434177

rs7111039

C

0.59354526

METTL15

Apoptotic process/rRNA base methylation

Top 10 genetic contributors to SA-DCCA

6

112149373

rs9384810

C

8.071861

FYN

Neuron migration/Synapse

1

44249916

rs917293

A

7.428208

ST3GAL3

Ganglioside biosynthetic process via lactosylceramide

5

82371910

rs1993947

A

7.083643

TMEM167A

Protein secretion

9

96352243

rs10992792

C

6.3167377

PHF2

Zinc ion bindind

1

44249485

rs917294

A

6.0538197

ST3GAL3

Ganglioside biosynthetic process via lactosylceramide

6

28299687

rs853676

C

5.521865

ZSCAN31

Metal ion binding

9

96358301

rs10821168

C

5.354203

PHF2

Zinc ion bindind

5

82363068

rs144860721

C

5.352993

TMEM167A

Protein secretion

11

44626461

rs4755851

C

5.296435

CD82

Protein binding

Back to article page