Fig. 1: Knockout of Smc3 gene in excitatory neurons during adulthood.
From: Sex-specific modulation of anxiety-like behavior by forebrain neuronal SMC3 in mice
A Representative pictures of hippocampus (dentate gyrus) in wild type and Smc3 knockout mice 5 weeks after tamoxifen treatment. Hippocampi were stained with antibodies for NeuN (neuronal marker), SMC3, and Hoechst (marker for nuclie) Scale bars present 100 μm. B quantification of SMC3 positive cells in dentate gyrus of both groups (two-sided t-test WT, n = 8; cKO, n = 12; ****P < 0.0001). C Representative pictures of Cortex cells in wild type and Smc3 knockout mice 5 weeks after tamoxifen treatment; Scale bars present 5μm. Arrows point to NeuN positive cells.
