Fig. 2: Structural and functional neuroimages of a healthy and an AD brain. | Translational Psychiatry

Fig. 2: Structural and functional neuroimages of a healthy and an AD brain.

From: Fueling the brain - the role of apolipoprotein E in brain energy metabolism and its implications for Alzheimer’s disease

Fig. 2

FDG-PET (upper row,) β-amyloid-PET (second row), tau-PET (third row) and structural MRI images in the respective horizontal (left), sagittal (middle) and coronal (right) view from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. AD subjects show reduced FDG-PET intensity, increased amyloid- and tau-PET signals as well as brain atrophy in MRI. HCS: Female, 67 y, MMSE 30, APOE3/3, amyloid tracer: [18F]florbetapir, tau tracer: [18F]flortaucepir; AD subject: Male, 75 y, MMSE 20, APOE3/4, amyloid tracer: [18F]florbetaben, tau tracer: [18F]flortaucepir; Colorbars: Standard visual display with comparable reference tissue color level.

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