Fig. 3: Treatment-induced alterations in dorsolateral prefrontal cortex (DLPFC), posterior cingulate cortex (PCC), and insula cortex (IC) connectivity and their links with symptom reduction in major depressive disorder (MDD). | Translational Psychiatry

Fig. 3: Treatment-induced alterations in dorsolateral prefrontal cortex (DLPFC), posterior cingulate cortex (PCC), and insula cortex (IC) connectivity and their links with symptom reduction in major depressive disorder (MDD).

From: Early treatment-related changes in dorsolateral prefrontal cortex activity and functional connectivity as potential biomarkers for antidepressant response in major depressive disorder

Fig. 3

A Regions of interest (ROIs) that were created in DLPFC, PCC, and IC; B Correlations between changes in DLPFC- IC functional connectivity (FC) in the theta-band and alpha-band and change in 21-item Hamilton Depression Rating Scale (HAMD-21) scores in patients with MDD. Note. L left, R right.

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