Fig. 4: Moderating role of plasma pTau-181 in the relationship between salivary mtDNA and 18F-Florbetaben (FBB)-PET binding to Aβ deposits in the neocortex.

(A) Significant results projected onto the cortical surface. (B) Scatter plots depicting partial correlations between salivary mtDNA and peak vertices of cortical FBB binding in participants showing high (pink) and low (green) plasma pTau-181 levels, adjusted for age and sex. L: left, R: Right.